Novedades Bibliográficas

[Comment] Offline: UHC—one promise and two misunderstandings

The Lancet - Sáb, 07/04/2018 - 00:00
On April 7, 2018, World Health Day, WHO launches a new campaign—Universal Health Coverage: Everyone, Everywhere. This is a noble cause. As the agency notes: half the world's population is unable to access essential health services; 100 million people are pushed into extreme poverty each year because of out-of-pocket expenditures on health; and catastrophic spending on illness and disease is a truly global problem. Therefore, “our next historic achievement is right in front of us: health for all humankind…Together, we can make universal health coverage happen in our lifetime.” The campaign will run throughout 2018.

[World Report] Violence rife in Mexico, affecting medical community

The Lancet - Sáb, 07/04/2018 - 00:00
The medical community is caught in the middle of omnipresent violence in Mexico, where homicide rates reached record levels in 2017. David Agren reports from Villahermosa.

[World Report] Progress in influenza surveillance in Africa

The Lancet - Sáb, 07/04/2018 - 00:00
Influenza could be an overlooked cause of death in Africa. Although rapid progress has been made, there is still limited surveillance capacity to assess the risk of epidemic. Andrew Green reports.

[Perspectives] A neurologist's detective stories

The Lancet - Sáb, 07/04/2018 - 00:00
Western medicine is organised into silos. Faced with a patient requiring specialist advice, a general practitioner or emergency doctor has to make a call about where to direct them. Sometimes, the right clinical destination is obvious: a compound thigh fracture will always need an orthopaedic surgeon. But many patients fall foul of this rigid system. An individual complaining of dizziness might get bounced from ENT, to cardiology, to neurology, to psychiatry before achieving a diagnosis.

[Perspectives] Getting back in touch

The Lancet - Sáb, 07/04/2018 - 00:00
Clinicians and patients are getting out of touch with one another. When I was a medical student, I spent hours with patients, examining them on the ward, taking blood, and assisting at operations. At first I felt clumsy, inept, and embarrassed at the prospect of physical contact, for touch is surrounded by social conventions and taboos that are difficult to break through. But gradually, through practice, I became more confident. Touching people stopped feeling strange. Ostensibly, the purpose of these examinations was to gather diagnostic information that I would relay to senior clinicians.

[Perspectives] WHOse health agenda? 70 years of struggle over WHO's mandate

The Lancet - Sáb, 07/04/2018 - 00:00
Like any milestone, WHO's 70th anniversary offers an opportunity to reflect on its past trajectory and chart the challenges ahead. WHO's promising mandate for health cooperation, forged amid a short-lived post-war optimism, mapped out a world of possibilities. Yet its realisation has been limited across distinct eras by complex geopolitical, economic, and institutional pressures, ranging from the Cold War rivalry between US and Soviet blocs to contemporary assaults on WHO's independence by powerful private actors.

[Obituary] John Sulston

The Lancet - Sáb, 07/04/2018 - 00:00
Nobel Prize winner for work on Caenorhabditis elegans and a leader in human genome research. Born in Fulmer, UK, on March 27, 1942, he died on March 6, 2018, from complications of stomach cancer, aged 75 years.

[Correspondence] Polio transition: overlooked challenges

The Lancet - Sáb, 07/04/2018 - 00:00
The reduction in the number of poliomyelitis cases by more than 99% is an extraordinary success of the global community. In their Comment, Michel Zaffran and colleagues (Jan 6, p 11)1 assume that eradication will be achieved soon and focus on strategies to ensure that poliovirus will not be reintroduced into a polio-free world.2

[Correspondence] On the misuses of medical history

The Lancet - Sáb, 07/04/2018 - 00:00
A surprising amount of bad history passes peer review in the sciences and medicine. What do we mean by bad history? One example would be the misuse of historical images. Many images of so-called plague used in scientific publications depict patients suffering from leprosy.1 Another example is when commonly repeated claims about historical people or events are lifted from earlier scientific or medical writings, without checking whether professional historical scholarship has revised earlier interpretations.

[Correspondence] C1 esterase inhibitor concentrates and attenuated androgens

The Lancet - Sáb, 07/04/2018 - 00:00
Marc A Riedl and colleagues (July 25, 2017, p 1595)1 conducted a phase 2, multicentre, randomised, double-blind, placebo-controlled crossover trial in 32 patients to test the prophylactic efficacy of recombinant human C1 esterase inhibitor for hereditary angio-oedema. Once or twice weekly administration of recombinant human C1 esterase inhibitor (50 IU/kg) reached the primary endpoint (reduced number of attacks) in an intention-to-treat analysis.

[Correspondence] C1 esterase inhibitor concentrates and attenuated androgens – Authors' reply

The Lancet - Sáb, 07/04/2018 - 00:00
We thank Yannick D Muller and colleagues for their interest in our Article1 describing results from a randomised, double-blind, placebo-controlled study with the use of recombinant human C1 esterase inhibitor for prophylaxis of hereditary angio-oedema.

[Department of Error] Department of Error

The Lancet - Sáb, 07/04/2018 - 00:00
Khanna D, Denton CP, Angelika Jahreis A, et al. Safety and efficacy of subcutaneous tocilizumab in adults with systemic sclerosis (faSScinate): a phase 2, randomised, controlled trial. Lancet 2016; 387: 2630–40—In table 3 of this Article (published online first on May 5, 2016), the p value (placebo vs tocilizumab) for a decrease of 4·7 units or more at 48 weeks should have been 0·25. The interpretation of these data remains unchanged. This correction has been made online as of April 5, 2018.

[Department of Error] Department of Error

The Lancet - Vie, 06/04/2018 - 00:30
The Lancet. Dementia in the UK: preparing the NHS for new treatments. Lancet 2018; 391: 1237— In the second sentence of this Editorial, the cost of dementia to the National Health Service in the UK should have been £26 billion. This correction has been made to the online version as of April 5, 2018.

[Editorial] Dementia in the UK: preparing the NHS for new treatments

The Lancet - Sáb, 31/03/2018 - 00:00
Dementia is a devastating disease that brings fear, confusion, and loneliness to the lives of patients and their families. Today, around 850?000 people in the UK are living with dementia, costing the National Health Service (NHS) and UK society more than £26 million annually. By 2025, it is estimated that over 1 million people in the UK will be affected, with the prevalence and costs of care for these patients expected to double by 2050. These are worrisome figures given the absence of any safe, clinically effective, disease-modifying therapy for Alzheimer's disease or other forms of dementia.

[Editorial] Good news for the world's newest nation

The Lancet - Sáb, 31/03/2018 - 00:00
Despite South Sudan's crippling civil war, the country has interrupted the transmission of Guinea worm disease, announced the Carter Center on March 21. This disease is now on the edge of eradication, with only six countries reporting low rates of infection.

[Editorial] Cybersecurity and patient protection

The Lancet - Sáb, 31/03/2018 - 00:00
Network-connected devices and data are vulnerable to attack, exploitation, and unintended loss. The alleged harvesting of profiles from 50 million people by Cambridge Analytica through friend networks on Facebook is the most recent and egregious example. In May, 2017, the WannaCry ransomware that infected more than 200?000 computers across 100 countries also infiltrated a third of National Health Service trusts, and brought some services to a standstill. Yet, despite agreement on the need for better cyber hygiene (risk management and online health), there is no consensus on what form it should take.

[Comment] Transparency of retracting and replacing articles

The Lancet - Sáb, 31/03/2018 - 00:00
Journal editors are responsible for the integrity of the published record and must correct it when necessary. They are getting better at this job, as evidenced by journal retraction policies1 and numbers of article retractions.2 Most retractions are due to misconduct, but about 20% are retracted because of an unintentional error or methodological flaw.2 To credit the correction of an honest error and avoid stigmatisation of authors, journals have begun a practice of retraction with republication of a corrected article.

[Comment] Offline: The Palestinian health predicament worsens

The Lancet - Sáb, 31/03/2018 - 00:00
The United Nations Relief and Works Agency (UNRWA), which administers health services to 5·3 million Palestinian refugees through 143 primary health facilities, is in acute crisis. After President Trump cut almost US$300 million from UNRWA's 2018 budget, services will run out of money by the end of May. Irrespective of one's views about the complex politics of the Middle East, America's decision to threaten the provision of basic health care to millions of dependent people seems utterly cruel. This emergency was a major theme of last week's annual Lancet Palestinian Health Alliance (LPHA) scientific meeting, held in Beirut, Lebanon.

[World Report] Gairdner Awards 2018 honour GBD studies

The Lancet - Sáb, 31/03/2018 - 00:00
Creators of the GBD studies look back at almost two decades since the first iteration. Other awards recognised the fields of optogenetics, epigenetics, and lung cancer research. Brian Owens reports.

[World Report] What does the GDPR mean for the medical community?

The Lancet - Sáb, 31/03/2018 - 00:00
The General Data Protection Regulation will start in May across the European Union, but doubts are being cast on how prepared researchers and clinicians are. Becky McCall reports.
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