Novedades Bibliográficas

An untrustworthy government during a pandemic—a lethal combination

British Medical Journal - Mié, 20/04/2022 - 18:21
At a time when millions of people were legally restricted from seeing their loved ones, thousands were in hospital, and the body count was growing by the day, the leader of the UK’s pandemic...

Novel treatments in B cell non-Hodgkin’s lymphomas

British Medical Journal - Mié, 20/04/2022 - 10:46
ABSTRACTThe improved understanding of lymphoma biology and recent advances in the field of cancer immunology have paved the way for the development of many effective small molecule inhibitors and...

Health leaders urge PM to meet hunger striker’s demand that MPs be briefed on climate change

British Medical Journal - Mié, 20/04/2022 - 09:01
Senior health professionals, including the current and former editors in chief of The BMJ, have written to Prime Minister Boris Johnson urging him to commit to holding an urgent briefing for all MPs...

Meningitis vaccine could protect against gonorrhoea, studies find

British Medical Journal - Mar, 19/04/2022 - 17:23
The meningitis vaccine could be used to provide some protection against gonorrhoea, researchers have said.In a collection of studies published in Lancet Infectious Diseases they reported that two...

Covid-19: Mask mandate is struck down although US cases are rising

British Medical Journal - Mar, 19/04/2022 - 17:11
Covid-19 cases in the US rose by 43% over the past two weeks, with especially high rates seen in north eastern states, according to the New York Times coronavirus tracker.1Cases rose to a seven day...

Medicare’s decision not to fund Aduhelm changes landscape for US pharma industry

British Medical Journal - Mar, 19/04/2022 - 15:36
The decision by the agency responsible for Medicare to restrict coverage of Biogen’s Alzheimer’s drug aducanumab (Aduhelm) to patients enrolled in randomised controlled trials has soured the...

Clinical leadership is a difficult balancing act

British Medical Journal - Jue, 14/04/2022 - 13:06
Kar writes about the challenges of NHS leadership.1 It takes a very special person to become a clinical leader if the role has a management component.In days gone by, clinicians’ requests for funding...

Covid-19: Health leaders accuse government of ignoring crisis in NHS

British Medical Journal - Jue, 14/04/2022 - 12:46
The BMA has accused the UK government of “burying its head in the sand” over current high levels of covid-19 and the threat they pose to health services and recovery plans.It warned that the...

The health community must resist the UK’s expansion of oil and gas

British Medical Journal - Jue, 14/04/2022 - 12:11
When it comes to the health impacts of the climate crisis, every degree matters. This fact has been keenly emphasised in the recent instalment of the sixth Intergovernmental Panel on Climate Change...

Measuring what counts to improve quality of care

British Medical Journal - Jue, 14/04/2022 - 11:51
In the US in 1961, Robert McNamara joined the Kennedy administration as secretary of defence, bringing with him a strong track record in the application of metrics to complex problems. During the...

Why the world has no universal biosafety standards

British Medical Journal - Jue, 14/04/2022 - 11:31
In late November 2021, after weeks of no confirmed community transmission of SARS-CoV-2, Taiwan’s Central Epidemic Command Center held a special evening press conference to announce an unusual...

Johnson’s bigger crime is failing to take the nation’s health seriously enough

British Medical Journal - Jue, 14/04/2022 - 11:26
The ideal of living longer and healthier has proved to be fool’s gold. Instead, people are living for longer but with chronic disease and a poor quality of life. The unwellness industry in older age...

Making Prescription Drugs More Affordable Under the Biden Administration

JAMA - Mar, 02/03/2021 - 02:00
This Viewpoint discusses policies the Biden administration can enact to reduce costs, including benchmarking Medicare Part B drug payments to the lowest price paid in similar countries, preventing Part D plans from negotiating confidential rebates with manufacturers, and patent reform to promote generic drug use.

Addressing Excess Health Care Pricing With Backstop Price Caps

JAMA - Mar, 02/03/2021 - 02:00
This Viewpoint reviews evidence that higher hospital prices reflect greater market power more than higher-quality services and proposes that backstop price caps can mitigate harms from the most excessive prices without constraining or distorting competitive health care markets.


JAMA - Mar, 02/03/2021 - 02:00

Diagnosis and Treatment of Irritable Bowel Syndrome

JAMA - Mar, 02/03/2021 - 02:00
This narrative review summarizes the epidemiology, pathophysiology, diagnosis, management, and prognosis of irritable bowel syndrome.

It’s Not Your Fault—Forgiveness in Illness and Death

JAMA - Mar, 02/03/2021 - 02:00
In this narrative medicine essay an infectious diseases physician shares the sense of forgiveness she brings to anyone possibly involved in COVID-19 transmission, having learned as a child the healing power of family absolution after she witnessed the death of a cousin.

Reason for Everything

JAMA - Mar, 02/03/2021 - 02:00
I will work. I will work without a mask. I will mask the work of courage. I will say there is a reason, bury my aunt, and say it again. I will walk on any street without a graveyard without a mask. I will let our children play there. I will see them share the sand. I will let them touch each other. I will see them slip in soil. I will remember I played dead. I will forget two hundred thousand bodies. I will sift anything but ash.

Effect of Blinatumomab vs Chemotherapy on Event-Free Survival in Children With High-Risk First Relapse of B-Cell ALL

JAMA - Mar, 02/03/2021 - 02:00
This randomized trial compares the effects of blinatumomab, an antibody construct that links CD3+ T cells to CD19+ leukemia cells, vs consolidation chemotherapy as a third consolidation block before allogeneic hematopoietic stem cell transplant (HST) on event-free survival in children with high-risk first-relapse B-cell acute lymphoblastic leukemia (B-ALL).

Consolidation With Blinatumomab vs Chemotherapy in First Relapse of B-Cell Acute Lymphoblastic Leukemia

JAMA - Mar, 02/03/2021 - 02:00
This randomized trial compares the effects of postreinduction therapy consolidation using blinatumomab, an antibody construct that links CD3+ T cells to CD19+ leukemia cells, vs chemotherapy on disease-free survival among children, adolescents, and young adults with first relapse of B-cell acute lymphoblastic leukemia (ALL).
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