Updated recommendations for treating gonorrhea aim to combat rising drug resistance.

More than 81?000 people died of drug overdoses in the US between June 2019 and May 2020, a record-breaking number that CDC officials suggested is related to the coronavirus disease 2019 (COVID-19) pandemic.

This Viewpoint evaluates Biden’s health care proposals to help reduce the cost burden on patients with cancer should they be enacted legislatively.

This Viewpoint suggests that the COVID-19 pandemic provides an opportunity to build trust in science and update federal agencies to improve public health and poses questions and offers recommendations for consideration.

This narrative review summarizes the pathophysiology, diagnosis, and treatment of osteoarthritis (OA) of the hip and knee, including use of structured exercise, acetaminophen and NSAIDs, corticosteroid injections, and surgery to manage symptoms.

In this narrative medicine essay an internal medicine hospitalist explores what the new diagnosis of breast cancer means for her professional identity and considers how the COVID-19 pandemic facilitates the hiding of serious illness but also complicates disclosing the news to colleagues and friends.

Months we all gelled—pills, probes, we pried, we eyed you. Scouring echoes mottled like the Moon, I found your face. Eighteen weeks in, too soon to fly your flawed cocoon, our doctor spied your two feet thrust through. Though your mother tried a banked bed, buoying you, her water broke. The wits I lacked, her nurses lent. “Just stroke her hair, don't look,” they pled—so I complied. But when your cord got clamped, before you ceased your windless breaths, I should've made a stand: amidst those steel stirrups, laying a hand that said, “We love you Lincoln. Go in peace.” What now? Stroke prints inked by lifeless feet then? Too late. You'll never be that close again.

This JAMA Patient Page explains the medications (naltrexone, acamprosate, disulfiram) and behavioral treatments (cognitive behavior therapy [CBT]) used to manage alcohol use disorder.

This noninferiority trial compares the effects of a restrictive (hemoglobin ?8 g/dL) vs liberal (hemoglobin ?10 g/dL) transfusion strategy on 30-day cardiovascular events among adults with acute myocardial infarction (AMI) and anemia (hemoglobin 7-10 g/dL).

This population epidemiology study describes the prevalence of bicuspid aortic valve (BAV) and BAV subtypes, and of accompanying enlarged aortic diameter or coarctation, in Danish newborns born in Copenhagen 2016-2018.

This randomized trial compares the effects of high-intensity interval training, moderate continuous training, and guideline-based physical activity on change in peak oxygen consumption (V?o2) in patients with heart failure with preserved ejection fraction (HFpEF).

This Medical Letter review reproduces a Table summarizing key information about drugs for osteoarthritis published as part of a comprehensive review on the topic.

In Reply Mr Li and Dr Wang highlight valuable examples of regulation from other industries, including banking and insurance. We agree that best practices from these industries provide lessons for health care and that health system–level algorithmic stewardship should complement clear guidance and oversight from those with regulatory authority.

In Reply In response to our recent article about trends in BP control among US adults, Dr Kovell and colleagues emphasize the importance of hypertension control to reduce cardiovascular disease mortality in women and to prevent maternal morbidity and mortality. They note that women had a larger reduction in BP control between 2013-2014 and 2017-2018 compared with men.

In Reply Teaching hospitals continue to expand the number of resident physicians, exceeding the number of government-funded residency spots, without additional government funding. This is a clear signal that the marginal benefit of employing a resident physician, even in the absence of government funding, clearly exceeds the cost—a narrative at odds with the public advocacy for more federal GME support. We applaud the work done by Dr Royce and others analyzing the distribution of GME funding as it pertains to higher revenue–generating specialties and primary care. It is important to note that there are no nationally coordinated GME performance metrics, and the few that exist are ad hoc and unvalidated. While it is important to collect validated measures of performance for benchmarking programs, they should not be used to justify the GME program, and Congress should use these GME funds, which amount to billions of dollars, for higher priorities.

To the Editor The Viewpoint by Ms Eaneff and colleagues proposed the role of stewardship for predictive algorithms by benchmarking to best practices from other clinical areas of medicine. In our opinion, to ensure the equality and safety of predictive algorithms, the health system could also learn from the high standards in other industries in which quality control and supervision of predictive algorithms are well established.

To the Editor In their recent article, Dr Muntner and colleagues demonstrated that despite the 2017 American College of Cardiology/American Heart Association blood pressure (BP) guidelines recommending more intensive BP treatment, there was a striking decrease in BP control among US adults with hypertension from 2013-2014 to 2017-2018.

To the Editor In their recent Viewpoint, Dr Grischkan and colleagues provided a synopsis of the forces behind the contemporary financing of US graduate medical education (GME). They claimed that training of residents by teaching hospitals is a profitable endeavor. Supporting their position, the authors observed that more than 15?000 resident positions have been created since 2003, despite no increase in federal funding for these positions. Two points deserve further consideration.

This study examines the prevalence and outcomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among migrant workers in Singapore.