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Doctors mount resistance to Florida plan to end vaccine mandates, despite gagging

British Medical Journal - Vie, 31/10/2025 - 15:26

Doctors have urged Florida policymakers to reject plans to end childhood vaccine mandates, with others claiming they are being silenced on the matter by their institutions.On 3 September, Florida Surgeon General Joseph Ladapo announced that “the Florida health department is going to be working to end all vaccine mandates in Florida law.” He said, “Who am I, as a government or anyone else, to tell you what you should put in your body?”The announcement builds on the decision by Florida Governor Ron DeSantis during the covid-19 pandemic to reject vaccine and mask mandates for schools and workplaces.Florida is scheduled to end mandates for the hepatitis B, chickenpox, haemophilus influenza type b, and pneumococcal conjugate vaccines in December. The state’s health department said this will go into effect 90 days after the 3 September announcement.But before mandates can be removed for other vaccines, including those for measles, the change must be...

Categorías: Novedades Bibliográficas

Notorious GSK paroxetine adolescent depression trial is slapped with expression of concern amid legal action

British Medical Journal - Vie, 31/10/2025 - 14:01

A long criticised study on antidepressant use in adolescents has been flagged with an “expression of concern” by a leading academic journal after the launch of legal action.12George Murgatroyd III, a lawyer, is suing the publishing giant Elsevier, as well as the American Academy of Child and Adolescent Psychiatry, demanding the retraction of the 24 year old randomised trial.3Concerns about the widely cited article—including numerous demands for retraction456—have been circulating for almost as long as the paper itself, and the trial, known as Study 329, is regularly referred to as one of the best examples of spin, misreporting, and ghostwriting in industry funded medical research.In 2012 paroxetine’s manufacturer, GlaxoSmithKline (GSK), was fined a record $3bn (£2.27bn; €2.58bn), in part for illegally promoting paroxetine using the journal article.7 Published by the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP) in 2001, the article declared paroxetine “generally well tolerated...

Categorías: Novedades Bibliográficas

Methodological innovation and attitude change needed to improve inclusion of older people in research

British Medical Journal - Vie, 31/10/2025 - 11:46

Older people are systematically excluded from research, particularly clinical trials, despite having the highest health and care needs.1 The joint statement from research funders calls for a renewed commitment to ensuring better inclusion of older adults, particularly those with multiple long term health conditions.2But the statement doesn’t mention the growing number of older people with cognitive impairment who are often excluded altogether.3 This is primarily owing to the ethical, legal, and methodological complexities around involving participants who lack capacity to consent. A researcher we interviewed described this as “an insurmountable black box of horrendousness that I dare not go into” fearing that, if they get it wrong, they will be “illegal . . . and the ethics police will come for you.”4 This urgently needs to be tackled if we are to ensure better inclusion.Hope comes in the form of trials methodology research, which provides evidence based strategies to improve...

Categorías: Novedades Bibliográficas

Oestrogen to reverse silent osteoporosis

British Medical Journal - Vie, 31/10/2025 - 11:46

McNally raises the very important point of reversing silent osteoporosis.1 As a gynaecologist with a special interest in menopause care, I want to highlight the importance of hormone replacement therapy (HRT) for the prevention of osteoporosis in women.As McNally quotes, the prevalence of osteoporosis in women increases significantly from 2% at age 50 to 50% at 80. The average age of menopause in the UK is 51.2 Oestrogen has a profound effect on bone, and replacement of oestrogen in women has been seen to improve bone health in numerous studies—so much so that the British Menopause Society states that it should be considered a first line therapeutic intervention for the prevention of osteoporosis.34 This is especially true for women with premature ovarian insufficiency (whether iatrogenic or non-iatrogenic).5 Alongside discussions about balanced diet, vitamin D and calcium supplementation, reducing smoking, and improving exercise, HRT should be part of the consultation for...

Categorías: Novedades Bibliográficas

Conocimiento, colaboración y liderazgo en la batalla contra la infección y aparición de resistencias

Último número Revista Medicina Intensiva - Vie, 07/04/2023 - 22:15

F. Gordo Vidal
Med Intensiva. 2023;47:191-2

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