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[Editorial] The collapse of the Venezuelan health system

The Lancet - Sáb, 07/04/2018 - 00:00
When Hugo Chavez became Venezuela's new president in 1998, he promised to provide free health care to all and enshrined this right within Venezuela's new constitution, rewritten in 1999. Progress was rapid and initial results were promising: according to the World Bank, life expectancy at birth rose from 71·8 to 74·1 years for both genders and infant mortality fell from 26·7 to 14·6 deaths per 1000 live births between 1998 and 2013, the period of Chavez's rule. Success was recognised on the international stage and Venezuela achieved most of the UN's Millennium Development Goals set for 2010.

[Editorial] Privatising versus prioritising veterans' health

The Lancet - Sáb, 07/04/2018 - 00:00
On March 28, President Donald Trump relayed on Twitter that Ronny L Jackson, personal physician to the president and a rear admiral in the US Navy, but with no prior experience in administration, would replace Veterans Affairs (VA) Secretary David Shulkin. The announcement was met with shock and dismay as Shulkin, who had been at the VA since 2015 and who was the sole holdover from the Obama years, was well regarded by Republicans and Democrats alike. Trump himself had even referred to Shulkin as “our David”, an unusual term of endearment for anyone from the previous administration.

[Editorial] Health-care system transition in China

The Lancet - Sáb, 07/04/2018 - 00:00
On March 27, the National Health Commission replaced China's National Health and Family Planning Commission (NHFPC) as the ministry responsible for health. The new commission is now headed by Ma Xiaowei, who was the former deputy head of the dismantled NHFPC. Chinese media have described Xiaowei as the person who understands China's health and hospital situation best, owing to his strong background in medicine. Since his graduation from the medical treatment department of China Medical University in 1982, Xiaowei has served many key roles in various health sectors such as the president of the First Affiliated Hospital of China Medical University and director of Liaoning Provincial Health Department.

[Comment] Clinical Pictures in The Lancet: a good eye for detail

The Lancet - Sáb, 07/04/2018 - 00:00
A key part of medical training is developing the ability to recognise physical signs of illness in a patient and associate them with the causative pathology. The acquisition of this skill, through training and experience, marks the transition of student to clinician. In recent years, the required repertoire has changed, expanding to include recognition of pathological and radiological signs. But the passing of this diagnostic expertise from one generation to the next remains remarkably unchanged across the globe.

[Comment] Measuring Humanity: hip-hop as evidence for health inequalities

The Lancet - Sáb, 07/04/2018 - 00:00
Dear Human (video), a hip-hop video was developed as part of the project Measuring Humanity.1 Working with marginalised groups, the participant-led research programme uses bottom-up creative community engagement to challenge policy makers and academics to reassess what counts as evidence when developing policies, practices, and recommendations. The video features rapping written using co-produced data from marginalised community members, health and voluntary sector practitioners, and researchers.

[Comment] Offline: UHC—one promise and two misunderstandings

The Lancet - Sáb, 07/04/2018 - 00:00
On April 7, 2018, World Health Day, WHO launches a new campaign—Universal Health Coverage: Everyone, Everywhere. This is a noble cause. As the agency notes: half the world's population is unable to access essential health services; 100 million people are pushed into extreme poverty each year because of out-of-pocket expenditures on health; and catastrophic spending on illness and disease is a truly global problem. Therefore, “our next historic achievement is right in front of us: health for all humankind…Together, we can make universal health coverage happen in our lifetime.” The campaign will run throughout 2018.

[World Report] Violence rife in Mexico, affecting medical community

The Lancet - Sáb, 07/04/2018 - 00:00
The medical community is caught in the middle of omnipresent violence in Mexico, where homicide rates reached record levels in 2017. David Agren reports from Villahermosa.

[World Report] Progress in influenza surveillance in Africa

The Lancet - Sáb, 07/04/2018 - 00:00
Influenza could be an overlooked cause of death in Africa. Although rapid progress has been made, there is still limited surveillance capacity to assess the risk of epidemic. Andrew Green reports.

[Perspectives] A neurologist's detective stories

The Lancet - Sáb, 07/04/2018 - 00:00
Western medicine is organised into silos. Faced with a patient requiring specialist advice, a general practitioner or emergency doctor has to make a call about where to direct them. Sometimes, the right clinical destination is obvious: a compound thigh fracture will always need an orthopaedic surgeon. But many patients fall foul of this rigid system. An individual complaining of dizziness might get bounced from ENT, to cardiology, to neurology, to psychiatry before achieving a diagnosis.

[Perspectives] Getting back in touch

The Lancet - Sáb, 07/04/2018 - 00:00
Clinicians and patients are getting out of touch with one another. When I was a medical student, I spent hours with patients, examining them on the ward, taking blood, and assisting at operations. At first I felt clumsy, inept, and embarrassed at the prospect of physical contact, for touch is surrounded by social conventions and taboos that are difficult to break through. But gradually, through practice, I became more confident. Touching people stopped feeling strange. Ostensibly, the purpose of these examinations was to gather diagnostic information that I would relay to senior clinicians.

[Perspectives] WHOse health agenda? 70 years of struggle over WHO's mandate

The Lancet - Sáb, 07/04/2018 - 00:00
Like any milestone, WHO's 70th anniversary offers an opportunity to reflect on its past trajectory and chart the challenges ahead. WHO's promising mandate for health cooperation, forged amid a short-lived post-war optimism, mapped out a world of possibilities. Yet its realisation has been limited across distinct eras by complex geopolitical, economic, and institutional pressures, ranging from the Cold War rivalry between US and Soviet blocs to contemporary assaults on WHO's independence by powerful private actors.

[Obituary] John Sulston

The Lancet - Sáb, 07/04/2018 - 00:00
Nobel Prize winner for work on Caenorhabditis elegans and a leader in human genome research. Born in Fulmer, UK, on March 27, 1942, he died on March 6, 2018, from complications of stomach cancer, aged 75 years.

[Correspondence] Polio transition: overlooked challenges

The Lancet - Sáb, 07/04/2018 - 00:00
The reduction in the number of poliomyelitis cases by more than 99% is an extraordinary success of the global community. In their Comment, Michel Zaffran and colleagues (Jan 6, p 11)1 assume that eradication will be achieved soon and focus on strategies to ensure that poliovirus will not be reintroduced into a polio-free world.2

[Correspondence] On the misuses of medical history

The Lancet - Sáb, 07/04/2018 - 00:00
A surprising amount of bad history passes peer review in the sciences and medicine. What do we mean by bad history? One example would be the misuse of historical images. Many images of so-called plague used in scientific publications depict patients suffering from leprosy.1 Another example is when commonly repeated claims about historical people or events are lifted from earlier scientific or medical writings, without checking whether professional historical scholarship has revised earlier interpretations.

[Correspondence] C1 esterase inhibitor concentrates and attenuated androgens

The Lancet - Sáb, 07/04/2018 - 00:00
Marc A Riedl and colleagues (July 25, 2017, p 1595)1 conducted a phase 2, multicentre, randomised, double-blind, placebo-controlled crossover trial in 32 patients to test the prophylactic efficacy of recombinant human C1 esterase inhibitor for hereditary angio-oedema. Once or twice weekly administration of recombinant human C1 esterase inhibitor (50 IU/kg) reached the primary endpoint (reduced number of attacks) in an intention-to-treat analysis.

[Correspondence] C1 esterase inhibitor concentrates and attenuated androgens – Authors' reply

The Lancet - Sáb, 07/04/2018 - 00:00
We thank Yannick D Muller and colleagues for their interest in our Article1 describing results from a randomised, double-blind, placebo-controlled study with the use of recombinant human C1 esterase inhibitor for prophylaxis of hereditary angio-oedema.

[Department of Error] Department of Error

The Lancet - Sáb, 07/04/2018 - 00:00
Khanna D, Denton CP, Angelika Jahreis A, et al. Safety and efficacy of subcutaneous tocilizumab in adults with systemic sclerosis (faSScinate): a phase 2, randomised, controlled trial. Lancet 2016; 387: 2630–40—In table 3 of this Article (published online first on May 5, 2016), the p value (placebo vs tocilizumab) for a decrease of 4·7 units or more at 48 weeks should have been 0·25. The interpretation of these data remains unchanged. This correction has been made online as of April 5, 2018.

[Department of Error] Department of Error

The Lancet - Vie, 06/04/2018 - 00:30
The Lancet. Dementia in the UK: preparing the NHS for new treatments. Lancet 2018; 391: 1237— In the second sentence of this Editorial, the cost of dementia to the National Health Service in the UK should have been £26 billion. This correction has been made to the online version as of April 5, 2018.

[Editorial] Dementia in the UK: preparing the NHS for new treatments

The Lancet - Sáb, 31/03/2018 - 00:00
Dementia is a devastating disease that brings fear, confusion, and loneliness to the lives of patients and their families. Today, around 850?000 people in the UK are living with dementia, costing the National Health Service (NHS) and UK society more than £26 million annually. By 2025, it is estimated that over 1 million people in the UK will be affected, with the prevalence and costs of care for these patients expected to double by 2050. These are worrisome figures given the absence of any safe, clinically effective, disease-modifying therapy for Alzheimer's disease or other forms of dementia.

[Editorial] Good news for the world's newest nation

The Lancet - Sáb, 31/03/2018 - 00:00
Despite South Sudan's crippling civil war, the country has interrupted the transmission of Guinea worm disease, announced the Carter Center on March 21. This disease is now on the edge of eradication, with only six countries reporting low rates of infection.
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